12/14/2023 0 Comments Creatinine istat resultsYour GP of Nephrologist will monitor your eGFR regularly, as a declining eGFR is a sign that your kidney disease is getting worse.įor more information about eGFR and what your eGFR number mean, please refer to our eGFR fact sheet.Ī value below 60mL/min/1.73m2 suggests some loss of kidney function. eGFR is the best measure of how well your kidneys are working and in Australia, these results are reported on blood test results for individuals aged 18 years and over. Your eGFR is roughly equivalent to the degree of kidney function you have, so an eGFR of 60 would mean that your kidneys are only working at about 60%. The equation uses the amount of Creatinine (a waste product) in your blood, as well as your sex and age to work out an estimated GFR (eGFR). You GFR is very difficult to measure in the body, so it is calculated using an equation. The degree to which your kidneys are working and filtering your blood is measured by your Glomerular Filtration Rate or GFR. The filters in your kidney work much the same way that a water filter works - they clean your blood by removing the waste products that then leave the body via the urine, and they return the clean blood to keep circulating around your body. Your kidney function is determined by how well these filters are working. However, results were on average slightly higher than for the Beckman Synchron CX7 method.Your kidneys are made up of thousands of tiny filters called Nephrons. The i-STAT creatinine method is simple and rapid and our evaluation showed satisfactory accuracy and precision. Assays of hemodialysate and peritoneal effluent were also satisfactory. We assessed the recommended creatinine correction for variation in PCO2 above and below 40 mm Hg, but our results did not suggest the need for such a correction in our range of 27-64 mm Hg omission would remove a major method disadvantage. The correlation coefficient between the two methods was 0.99, the slope 1.0 and the intercept -5.0 micromol/l (-0.06 mg/dl). The difference between the two means was 2.6% and the mean of all differences was 10.9% with i-STAT results higher, especially when blood creatinine values were < 100 micromol/l (1.1 mg/dl) indicating the need for a slightly higher upper limit of the normal range. To assess accuracy, we compared results of 149 tests by i-STAT and Beckman Synchron CX7 methods. Imprecision studies gave excellent results, including those for reproducibility of 6 solutions with a mean of 10 repeats and coefficients of variation (CVs) of 0.4-3.4%, and also the mean of the differences between 33 duplicate blood specimens which was 2.2% of the specimen mean. Good results have already been reported using this analyzer for 10 methods including electrolytes, TCO2, pH, PCO2, bicarbonate, glucose, hemoglobin and urea for uremic blood, hemodialysate and peritoneal effluent.Įvaluation included study of imprecision and accuracy. We evaluated a new, 2-min blood creatinine method using the hand-held i-STAT analyzer.
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